Anti-Human PLAUR Recombinant Antibody (2.19.2)
CAT#: TAB-238CQ
The human monoclonal antibody binds to the uPAR with high affinity (KD=115 pM) and can inhibit uPAR-induced cell adhesion and invasion.
Published Data
Tested Data
Gene Expression
Inhib
Figure 1 A line graph showing the inhibitory effect of fifteen anti-uPAR monoclonal antibodies in a plasminogen activation inhibition assay.
WB
Figure 2 The results of epitope binding analysis of anti-human uPAR mAbs by Western Blotting.
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SDS-PAGE
Figure 1 Anti-Human PLAUR Recombinant Antibody (TAB-238CQ) in SDS-PAGE
SDS-PAGE analysis of TAB-238CQ in non-reduced (Lane 1) and reduced (Lane 2) conditions.
SEC-HPLC
Figure 2 Anti-Human PLAUR Recombinant Antibody (TAB-238CQ) in HPLC
HPLC analysis of TAB-238CQ shows the purity is>95%.
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73533/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_A_5_6.jpg
Normal Tissue
Figure 7 Bone marrow
Hematopoietic cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50843/117396_B_5_4.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000011422-PLAUR
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Specifications
- Immunogen
- Soluble uPAR and cell-bound uPAR
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human, Cynomolgous monkey
- Clone
- 2.19.2
- Applications
- Inhib, WB
- Related Disease
- Cell adhesion and invasion
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
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(Creative Biolabs Cat# TAB-238CQ, RRID: AB_3111895)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 2.19.2"
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-355 | Mouse Anti-PLAUR Recombinant Antibody scFv Fragment (PSBL-355) | WB, ELISA, FuncS | Mouse scFv |
| PSBL-356 | Mouse Anti-PLAUR Recombinant Antibody (clone 8B12); scFv Fragment | WB, ELISA, IF, FuncS | Mouse scFv |
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| HPAB-0616YY-S(P) | Human Anti-PLAUR Recombinant Antibody (clone H5L5); scFv Fragment | ELISA, FC, WB | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-355 | Mouse Anti-PLAUR Recombinant Antibody Fab Fragment (PFBL-355) | WB, ELISA, FuncS | Mouse Fab |
| PFBL-356 | Mouse Anti-PLAUR Recombinant Antibody (clone 8B12); Fab Fragment | WB, ELISA, IF, FuncS | Mouse Fab |
| HPAB-0175-YC-F(E) | Mouse Anti-PLAUR Recombinant Antibody (clone 7G1); Fab Fragment | ELISA, WB | Mouse Fab |
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|---|---|---|---|
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